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Randomized phase II study of modified FOLFOX-6 in combination with ramucirumab or icrucumab as second-line therapy in patients with metastatic colorectal cancer after disease progression on first-line irinotecan-based therapy

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The ascorbate-glutathione pathway (Halliwell-Asada cycle) is an indispensible component of the ROS homeostasis mechanism of plants

The results showed that the changes in gene expression were associated with decreased lipid metabolism (mitochondria using lipids less for fuel) and alterations in the genes needed for energy production in the mitochondria