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[10] In EDS types I and II, cEDS and clEDS, causative mutations may involved the COL5A1, COL5A2, and tenascin-X genes and are implied to be in the COL1A2 gene

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Amide metabolism by rat S9 fractions Rat S9 metabolic systems are commonly used in the bacterial reverse mutation assay (Ames test) to assess the mutagenicity of compounds 22

There are interactions with the serotonin and GABA systems too, and some animal studies have shown anxiety-reducing effects

This method combines the advantages of solid-phase synthesis and synthetic biology methods, mainly to synthesize polypeptide chains, and then uses synthetic biology methods to complete the rest

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