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Ronnov-Jessen, L., Petersen, O

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In addition, neutral endopeptidase (NEP) plays a minor role in GLP-1 degradation by cleaving at six sites, Asp15-Val16, Ser18-Tyr19, Tyr19-Leu20, Glu27-Phe28, Phe28-Ile29 and Trp31-Leu32, within the central and C-terminal peptide domains [44]

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Those placed on a supervised exercise programme in addition to taking the GLP-1 liraglutide, were four times as likely to maintain weight loss of 10% or more a year after coming off the drug, compared to those on liraglutide alone

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