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Thus, we determined ER-stress response genes Xbp1 and the ER chaperone heat shock 70 kDa protein 5 (HSPA5, previously known as immunoglobulin heavy chain binding protein [BIP]), inflammation-responsive genes IL6 and IL1, and hypoxia-responsive genes hypoxia-inducible transcription factor 1 (HIF1) and GAPDH

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After reconstitution: Refrigerate (approximately 28 C) and follow your institutions SOPs for aliquoting, handling, and disposal

While the FDA existing regs are clear, recent signals from FDA introduced uncertainty