1 Background: metabolic-reproductive challenges of PCOS across lifespan 1.1 Epidemiology and reproductive impact Polycystic Ovary Syndrome (PCOS) is recognized not only as a reproductive disorder in women of childbearing age but also as a complex, lifelong cardiometabolic risk state ( Due to oligo-ovulation or amenorrhea, PCOS leads to a decline in natural conception rates ( This risk, superimposed with delayed childbearing, amplifies reproductive uncertainty
Schneider, E., et al., Dose-proportionality of oral thioctic acid--coincidence of assessments via pooled plasma and individual data
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Evidence from animal studies supports its anti-inflammatory and angiogenic effects in soft tissue recovery
The renoprotective role of autophagy activation in proximal tubular epithelial cells in diabetic nephropathy