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Ashley Capoot and Annika Kim Constantino explain more in their (linked) coverage yesterday for CNBC

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Researchers modeling repeat-dose experiments generally aim to reach steady-state concentrations after four to five half-lives of continuous administration

Farda B, Djebaili R, Vaccarelli I, Del Gallo M, Pellegrini M

J Steroid Biochem Mol Biol 141, 113-20 (2014)

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