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Q: What evidence supports its effects in animal models

Olson AK, Bouchard B, Zhu WZ, Chatham JC, Des Rosiers C (2020) First characterization of glucose flux through the hexosamine biosynthesis pathway (HBP) in ex vivo mouse heart

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Gout: High doses of vitamin B6 (pyridoxine) may increase uric acid levels and trigger gout attacks