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This gradual titration protocol improves tolerability and is consistent with FDA-approved dosing strategies for weight management [1] [3]

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Data synthesis and analysis Serum ammonia concentration and the number connection test (NCT) are both components of the widely used porto-systemic encephalopathy (PSE) index according to the West-Haven criteria.16 Considering the improvement might be significantly different for patients divided into different West Haven grades, subgroup analyses were performed by for dif ferent groups according to the West-Haven criteria

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The Journal of Neuroscience, 31, 1445314457

J Nanobiotechnol 23 , 685 (2025)