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Consider adding electrolytes if diarrhea is frequent

The corresponding ETDs (95% CI) in percentage points vs sitagliptin 100 mg were 0.2 (0.3, 0.1), 0.7 (0.8, 0.6) and 1.0 (1.1, 0.8), respectively

Some researchers hypothesize that the increased energy expenditure from glucagon activation means less of the caloric deficit needs to come from dietary restriction, which may be less catabolic to muscle tissue

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So, its important to take care of your muscle-mass and learn how to avoid muscle loss on Mounjaro

GLP-1 inhibits pancreatic alpha-cells, thus inhibiting glucagon secretion, although the exact mechanism by which it acts on alpha-cells is not fully understood