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It also mitigates mitochondrial oxidative stress by preventing glutathione depletion and reducing reactive oxygen species (ROS) production, thereby protecting against mitochondrial dysfunction (30, 36)

As a result of a decreased glomerular filtration rate, metabolic disorders and renin-angiotensin system activation, hypertension is often accompanied by DKD

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In contrast, yerba mate studies have shown minimal weight loss benefittypically less than 2 pounds over several monthsand only when paired with calorie restriction or exercise