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Some attempts have been made to activate human BAT by 3-adrenergic receptor (AR) agonists, since the 3-AR appears to be the main mediator of BAT activation in murine models

Increased serum resistin levels in patients with type 2 diabetes are not linked with markers of insulin resistance and adiposity

By targeting the exact pathophysiological drivers of these conditionsmicroglial activation, AMPA receptor excitotoxicity, and sympathetic over-arousalL-theanine presents a scientifically grounded, low-risk intervention for complex chronic illness

So I'm excited about that