When medically appropriate, treatment may include FDA-approved medications , such as: Mounjaro (tirzepatide) Zepbound FDA-approved for chronic weight management Ozempic (semaglutide) Wegovy FDA-approved for weight management Physician-supervised semaglutide or tirzepatide-based programs may also be available
However, diuretic-induced sodium depletion may also play an underrecognized role in glucose homeostasis
doi: 10.1007/s11172-014-0716-2
J Exp Med (2005) 201:71322
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Specifically, semaglutide led to a 4.3lb higher mean weight loss compared to dulaglutide [20]