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MNTs are polypeptides that contain four moieties, including a ligand that can be internalized to provide cell recognition and lead to receptor-mediated endocytosis, endosomolytic modules for escaping endosomes, a nuclear localization sequence (NLS) motif to recognize and bind to nuclear importins and transport them to the nucleus, and a carrier domain for effective drug delivery [109]

Furthermore, specific peptides optimize metabolic rate, preserve lean muscle mass, and modulate glucagon secretion

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Tumor cells harness this metabolic pathway to meticulously preserve redox equilibrium, which is essential for sustaining their viability, proliferation, and the perpetuation of cell division, thereby facilitating their relentless growth and expansion (189, 190)

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10.1080/15548627.2021.1984656 151 ZhuY.MassenS.TerenzioM.LangV.Chen-LindnerS.EilsR.et al (2013)