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The dashed black curves show the responses of GSH and fractional hepatocytes to rescue by the standard dose of NAC (36 mM) given over a 1 hour time period starting at two hours after the APAP dose

PET-negative (across the entire cohort, within the CI/CN subgroups, and specifically between CN PET-negative and CI PET-positive individuals)

unfortunately, it cannot be used to determine the actual percentage of MHb in the blood

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Abstract : Purpose : Glutathione depletion has been documented in several disease states, and exogenous administration has been hypothesized to have therapeutic potential for some conditions

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