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Similar to cagrilintide, pramlintide is primarily eliminated via the kidneys and, in a pharmacokinetic study in participants with type 1 diabetes, no statistically significant differences were noted in total (AUC 0- ) and peak ( C max ) exposure after administration of a single pramlintide 60 g dose in participants with mild, moderate or severe renal impairment compared with those with normal renal function, although inter-patient variability was high [20]
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When travelling, use an insulated medication bag with a cool pack (ensuring the pen does not come into direct contact with ice or frozen gel packs, which could cause freezing)
The wound depth was also lower in the test group 0.30 0.48 cm than the control group 0.54 0.86 cm ( p = 0.025)
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