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In the second phase of the study, where patients received crossover treatments, self-reported fatigue scores were once again reduced significantly for each treatment regimen: mean FSS decreased by 0.7 for ASA and by 1.6 for amantadine [177]

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Chem Sci

In contrast, HIF-2, which is more indicative of chronic hypoxia, increased steadily with prolonged hypoxia time (Fig

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