One of the primary concerns involves gastrointestinal issues, particularly cases of ileus or bowel obstruction, which can lead to hospitalization and, in extreme cases, require surgical intervention
Gastrointestinal adverse events were the most frequently reported side effects across all retatrutide dose groups , and they occurred primarily during the dose escalation phase of treatment
Injectable medications originally developed for the treatment of diabetes are also effective for weight loss, and have surged in popularity for this purpose around the world
This hormone helps with blood sugar regulation, slows gastric emptying (how quickly food leaves your stomach), and increases the feeling of fullness after eating
Reevaluate metabolic status prior to discontinuing and restarting GLP-1 therapy, measure HbA1c, electrolytes, and fasting glucose and document any insulin requirements to assist in safe resumption
UK Evidence and Guidance Wegovy (semaglutide 2.4 mg) is a GLP-1 receptor agonist licensed by the MHRA for weight management in adults with obesity or overweight with comorbidities