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Early increases in low-density lipoprotein (LDL)-cholesterol were reported with OCA treatment in the first month

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Each strain must be rigorously evaluated to confirm the absence of pathogenic traits, such as the ability to cause infection or produce toxins (142)

Calculation of encapsulation efficiency After a typical encapsulation experiment, PLGA pellets were collected by centrifugation at 12396 g for 20 minutes using a micro centrifuge (Eppendorf 5418, Hamburg, Germany)