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Senolytic elimination of senescent macrophages restores muscle stem cell function in severely dystrophic muscle
This can lead to significant weight loss over time as patients consume fewer calories, making it an effective component of a comprehensive weight management plan
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Gastrointestinal side effectsnausea, vomiting, constipation, and diarrheaoccur at similar rates across BMI ranges but may feel more disruptive when someone has less weight buffer and lower caloric tolerance
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