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Compound 3 was isolated by silica gel column chromatography using a dichloromethane/methanol (DCM:MeOH = 40:1, V/V) eluent (yield: 75%)

Not all fats affect the body in the same way

The weight loss that has been observed in animal models after repeated administration of oxyntomodulin and PYY has led to interest in developing these peptides as antiobesity therapies in humans

Both Ms Gooding and Dr Hungerford say they are increasingly hearing anecdotal reports of people with eating disorders seeking weight loss drugs

For example, studies involving GLP-1 RAs have been shown to reduce major adverse cardiovascular events in patients with T2DM