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Various cytokines are known to modulate the balance between humoral and cellular immune responses depending on eminence of antigen activation of B and T lymphocytes into antibody-producing plasma and T effector cells

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also reported that IL-1 significantly increased the expression of NGF and BDNF, while TNF- upregulated substance P in human NP cells

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As the body ages, glutathione levels will fall below whats needed for optimal immune function and other critical processes (6)