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They help you lose weight by slowing down gastric emptying, helping you feel fuller for longer and reducing overall caloric intake

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For weight loss specifically, Phase 2 trial data suggests retatrutide produces greater average weight loss (22-24%) compared to tirzepatide (18-22%) at maximum doses

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Beyond week 24: long-term tolerability The long-term side effect profile is reassuring for most researchers

Hypoglycemia manifests through symptoms like shaking, a fast heartbeat, sweating, anxiety, hunger, or dizziness