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The border is irregular and sharply demarcated

Comparative effects of the antioxidant glutathione with metformin and Diane-35 on hormonal, metabolic, and inflammatory indicators in a DHEA-induced PCOS rat model

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Am J Physiol 237(2):E185-191

A typical regimen might begin with doses as low as 0.1mg to 0.25mg weekly, gradually increasing based on individual response

Many studies confirm the correlation between exposure to chronic stress and the occurrence of oxidative stress and elevated markers of oxidative stress ( Studies using animals show that the long-term effects of cortisol can affect individual markers of oxidative stress (9294)