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The melanoma study discussed below provides the strongest evidence for this selective activity
Some are formulated for enhanced uptake, but generally they provide reduced, erratic impact
Other relevant interactions: Colchicine (used for gout) may affect B12 absorption with long-term use Chloramphenicol (rarely used antibiotic) may blunt the haematological response to B12 treatment Monitoring considerations: Patients taking loop or thiazide diuretics require careful monitoring when initiating B12 therapy in severe deficiency, due to the risk of hypokalaemia during rapid cell production
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Biomolecules 11:1515 Boohaker RJ, Lee MW, Vishnubhotla P, Perez JLM, Khaled AR (2012) The use of therapeutic peptides to target and to kill cancer cells
have demonstrated that BPC-157 can modulate NO production, counteracting both NO-synthase inhibitors and excess NO from nitric oxide donors
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