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Retatrutide is an investigational triple receptor agonist (GLP-1, GIP, glucagon) that remains unlicensed in the UK, with no MHRA approval, no NHS availability, and no BNF listing as of 20242025

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The BPC-157 sequence is a partial fragment of a larger gastric protein, Body Protection Compound, first characterised in published research in the 1990s

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The only other human study was in 2015

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People with untreated hypothyroidism should delay sermorelin until their thyroid condition is managed, because low thyroid hormone levels can make sermorelin ineffective (thyroid hormone is important for growth hormone action)

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Absence of COA documentation or reluctance to provide testing results raises immediate concerns

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