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Chl content and ALA-synthesizing capacity consistently remained wild-type-like ( Supplementary Figures 3B, C ) with the striking exception of GSAAT(C190S), which exhibited a significantly lower rate of ALA synthesis

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Those stories and more in tonight's Health Watch

Larger doses do not make up for missed days

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In general, phase I metabolizing enzymes catalyze reactions that increase the reactivity of hydrophobic (fat-soluble) compounds, preparing them for reactions catalyzed by phase II biotransformation enzymes