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Hippo signaling pathway The Hippo signaling pathway regulator transcription regulator 1 (TAZ) regulates ferroptosis through epithelial membrane protein 1 (EMP1)-NOX4, which means that ferroptosis may be a therapeutic target for renal cell carcinoma and other TAZ-activated tumors [88]

Recent work investigates detailed molecular mechanisms and cellular targets[11]

The Department of Digestion, Metabolism and Reproduction is funded by grants from the MRC, BBSRC, NIHR, an Integrative Mammalian Biology (IMB) Capacity Building Award, an FP7- HEALTH-2009-241592 EuroCHIP grant and is supported by the NIHR Biomedical Research Centre Funding Scheme