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Arendt et al., 2013)

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The choice depends on what you're treating and what your prescriber recommends

Lack of TRIM21 is associated with increased Ab production, indicating that auto-Abs-mediated perturbations of TRIM21 function may drive production of auto-Abs [202]

IGF-2 can act over its own receptor (IGF-2 receptorIGF-2R), which is a manose-6-phosphate transmembrane protein with undetermined actionsit is thought that it acts as a scavenger receptor by sequestering IGF-2 and IGF-1 from the extracellular medium and targeting them for destruction [103]