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Fatal liver damage can be prevented if the initial dose of NAC is administered within 8-12 hours of an APAP overdose

[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Baird M.F., Graham S.M., Baker J.S., Bickerstaff G.F

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Patients who habitually take excessive doses of acetaminophen (usually well in excess of 4 g per day) are more likely to develop renal failure along with hepatotoxicity

Even small amounts mixed into the solution destroy peptide function irreversibly

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