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Two small RCTs found greater efficacy from phenobarbital as compared to valproic acid for the treatment of benzodiazepine-refractory status epilepticus

Thats where peptide therapy comes in

Naltrexone is an opioid antagonist that blocks opioid receptors in the brain's reward center

4I and Supplementary Fig

In the hypothalamus , GLP-1 receptor activation influences key neuronal populations that control energy balance

Key regulators of this plasticity include the genes Arx and Dnmt1: their suppression in mice reprograms -cells into functional -like cells, though with limited secretory capacity (Matsuoka et al., 2017