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M.MoralesA.BlascoC.ColellA.MariM.Garcia-RuizC.et al (2005)

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Schilling A, Corey R, Leonard M, et al

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Improved Cognitive Function and Mood Supports Neurogenesis: IGF-1 receptors are present in the brain, and IGF-1 is involved in neurogenesis, or the growth of new brain cells, which can support cognitive function

Glutathione S -transferase P1 has also been proposed to have a non-catalytic role in promoting cell proliferation by binding to and inhibiting JNK (Adler et al, 1999) JNK activity is increased when GSTP1 activity is reduced, either by small molecule GSTP1 inhibitors or in GSTP1 null mice (Henderson et al, 1998)