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There is no published evidence suggesting lower doses are less safe mechanistically, they should carry lower risk of side effects

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Appendicitis did not increase risk of CC: MRC-IEU(OR:1.000, 95%CI:0.999-1.001, P=0.641), Neale lab(OR:1.000, 95%CI:1.000-1.001, P=0.319)

The Role of Antioxidants in Supporting Detoxification Processes Antioxidants can help support the body's detoxification processes by neutralizing free radicals and reducing oxidative stress, which can damage cells and impair detoxification mechanisms

10.1016/j.intimp.2021.107486 81 XingD.DuY.DaiK.LangS.BaiY.LiuG

Financial disclosure This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors