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As of January 5, 2026, there are now 3,063 pending lawsuits in the general GLP-1 MDL and 29 pending lawsuits the NAION MDL

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Anaphylaxis and angioedema have been reported with GLP-1 receptor agonists

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A 2023 analysis in Obesity noted that GLP-1 agonists maintain efficacy in patients on systemic steroids, though weight loss velocity may be reduced by 2030 percent compared to steroid-free patients