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Cancer can cause multiple changes in the genetic expression via DNA hypermethylation and hypomethylation, loss of genomes responsible for DNA methylation, modifications in histone, and modifications in miRNA expression, which invariably control genetic expressions [97,98,99]

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*Molecules.* 23(7):1733

For real-time calcium imaging assay, plates were incubated at 4 C for 2 days in the dark and then transferred to 22 C with a SD photoperiod for 67 days