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For type 2 diabetes, NICE recommends GLP-1 receptor agonists when triple oral therapy is ineffective and BMI is 35 kg/m or higher (with lower thresholds for certain ethnic groups)

Ketogenic diet reduces alcohol withdrawal symptoms in humans and alcohol intake in rodents

A similar effect was observed when cyclosporin A was replaced by the polyamine L-carnitine (slope 0.29 vs 0.53, P = 0.004) (Fig

Depletion of LARS B cell subsets by LARS gene ablation or Leu depletion can inhibit immune escape in CRC

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GLP-1based therapies improve glycemic control and promote weight loss, but they also appear to dampen systemic inflammation through both weight-dependent and weight-independent effects