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elegans by regulating the mTOR signaling pathway and suppressing the release of CCL11 cytokines, which are connected to age-related cellular and tissue impairments ( 2.6 Others The crosstalk between the gut and other organs can also facilitate the hypoglycemic effect of metformin

Extended Data Figure 5 A near-atomic resolution model of the hGLP-1rGLP-1RG s complex

Inhibition of the NLRP3 inflammasome using selective small-molecule inhibitors, such as MCC950 or OLT1177, has shown efficacy in suppressing excessive cytokine release and reducing infection-associated inflammation (Marchetti et al., 2018)

Single-target drugs often produce inconsistent results because biological systems are interconnected

Compared with the HCD group, the HCD + ALC group had significantly reduced plasma TC and TG levels (Figures 2E,F)

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