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10.3390/ijms19061626 101 KunjiE

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and a 2021 peer-reviewed review on NNMT in obesity and type 2 diabetes noting the absence of human clinical trials

[10] [3] This is why healthcare professionals emphasise the importance of proper diagnosis before starting supplementation

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This theoretically preserves the cytosolic pool of NAD+ (Nicotinamide Adenine Dinucleotide), which is critical for sirtuin activation and mitochondrial oxidative phosphorylation