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In order to detect a medium effect size of 0.625 (average accuracy increase of 0.08 and standard deviation of 0.128) for the primary outcome (MIFT accuracy), with an intra subject correlation of 0.3, a power of 80% a false positive rate set to 5%, and assuming a 30% dropout rate, the target sample size was 44 participants

Trial 5 Results at Week 26 in a Trial of Semaglutide Tablets Compared to Placebo in Patients with Moderate Renal Impairment a The intent-to-treat population includes all randomized patients including patients on rescue medication

These blood tests help track the safety and effectiveness of the treatment

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Knock-out of DCC1 triggered production of mitochondrial ROS