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In SA-deficient NahG plants, the same OTC treatment did not increase the accumulation of free SA, however, bound SA levels were slightly but significantly higher in treated plants, as compared to controls ( Figure S2 )

In case of failure, fluoroquinolone-containing therapy (PPI, levofloxacin, amoxicillin, and, in case of quadruple therapy, bismuth) or PPI-amoxicillin high-dose dual therapy (PPI twice daily and amoxicillin) should be used (Malfertheiner et al., 2022)

Kim M, Qie Y, Park J, Kim CH

Inhibiting ASCT2 by V-9302 enhances the therapeutic effect of MLN4924 on tumor growth (Zhou et al., 2022)

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Funding This research was supported by an Operating Grant (MOP142230) from the Canadian Institutes of Health Research (WGF), and salary support was provided by the Canadian Institutes of Health Research Fellowship Award (MFE-381806) (JMW)