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doi: 10.1136/ard-2022-222764 20 MaiuoloJOppedisanoFGratteriSMuscoliCMollaceV

Small sample sizes can make drugs look much more or less effective than what they really are

While the ongoing SURPASS clinical trial aims to elucidate the mechanistic underpinnings of the drug and the best dosages for treating patients of varying BMIs, its benefits cannot be understated

Selank is the more directly relevant peptide for anxiety-focused research

Furthermore, GPX4 expression was decreased in epilepsy but was increased in nerve injury after the use of iron death inhibitors (Mao et al., 2019)

However, despite these pharmacological advantages, several limitations hinder their clinical translation