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Start your intake Common Local and Injection-Site Reactions Local reactions at the injection site are the most frequently reported adverse effects

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First, the liver secretes increased amounts of cholesterol into bile while the gallbladder's contractility decreases, creating an environment conducive to cholesterol crystal formation

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From there, it goes straight to the liver via the portal vein for whats called "first-pass metabolism." The liver is the body's detoxification center, and it's ruthless with foreign compounds, often breaking them down before they ever reach the rest of the body