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Vitexin has been shown to reduce the quantity of M1 phenotype macrophages in healthy tissue adjacent to tumors, enhance M1 macrophage polarization within tumor tissue, and impede the progression from ulcerative colitis to colorectal cancer (174)

And theres kind of two elements to this

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The lower yield observed for HD may be attributed to the decomposition of volatile compounds due to the high temperature (~100 C) applied during extraction (~3 h)

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That rate was much higher than among patients using the medications for Type 2 diabetes, which makes sense: Diabetes is widely understood as a chronic condition, while many people still approach weight loss medication as something temporary