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Common side effects reported with retatrutide include: Nausea, vomiting, and diarrhoea (most frequent, particularly during dose escalation) Decreased appetite Constipation Injection site reactions Mild increases in heart rate Cagrilintide has demonstrated a generally well-tolerated profile, with gastrointestinal symptoms also being the most commonly reported adverse effects

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Fehrer, C

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Methods Patients diagnosed with clEDS by the national EDS service in the UK ( n = 21) and abroad ( n = 1) were asked for consent for publication of their clinical and molecular data