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Semaglutide activates GLP-1 receptors in the hypothalamus (appetite), brainstem (fullness/nausea), pancreas (insulin), stomach (gastric emptying), and targets in the heart, liver, and kidneys

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Novo Nordisk continues to build stable stock supplies over coming weeks and months [and] doctors should be prioritising Ozempic for patients living with uncontrolled type 2 diabetes. Semaglutide supplies in Australia have been under strain since May 2022, when the Therapeutic Goods Administration (TGA) first warned against off-label prescribing of the drug for obesity management

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Several factors shift your targets and strategies