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Acknowledgements We thank Simon Gilroy (Department of Botany, University of Wisconsin) for providing us with the GCaMP3 seeds

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Although it is quickly absorbed following oral administration, it has low bioavailability due to its ineffective absorption [39]

Structural characteristics: GHK-Cu supports tight copper chelation while maintaining aqueous solubility and compatibility with biological matrices, enabling reproducible dosing and consistent behavior in in vitro, ex vivo, and in vivo research systems