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Clin Chem 1986

Factores importantes que limitan la efectividad incluyen: Adaptacin metablica : el cuerpo se ajusta rpidamente a estmulos termognicos Efecto placebo : significativo en estudios de prdida de peso Variabilidad individual : respuesta gentica y metablica diferente Calidad del producto : contenido real versus etiquetado frecuentemente discrepante La posicin de organizaciones profesionales como la Academy of Nutrition and Dietetics y el Grupo de Trabajo de Servicios Preventivos de EE.UU

Standardized commercial formats cannot accommodate the full spectrum of how prescribers and patients now use these therapies

Khodir, M.A

Excessive consumption can cause intestinal upset