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Additionally, the R152H mutation in GPX4 is involved in the development of Sedaghatian-type spinal metaphyseal dysplasia, a rare and fatal disease in newborn babies

A degraded peptide mostly under-delivers, which quietly undermines treatment and makes it harder for your provider to judge whether a change in your plan is working

Circulating Tumor DNA (ctDNA) for Surveillance Liquid biopsy technologies to detect ctDNA from NF1-deficient or TP53-mutant clones are being developed for monitoring disease recurrence or transformation in high-risk NF1 patients