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Brains were fixed, cryoprotected, and sectioned for immunofluorescent labeling using anti-Fos antibodies and fluorescent secondary antibodies
Most therapeutic peptides are rapidly cleaved by gastric acid and luminal proteases (pepsin, trypsin, chymotrypsin) before meaningful absorption can occur
However, the peptide with the introduced palmitic acid exhibited a significantly reduced water solubility
Peptides are strings of amino acids smaller than a protein that often act as signaling molecules in our bodies and carry out many critical functions