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Direct Comparison Zepbound shows a clear advantage in average weight loss, producing roughly 7.6 percentage points more loss than Wegovy

The planned treatment analysis includes everyone assigned to a dose group regardless of whether they completed titration

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The accumulation of the protein fragment beta-amyloid (plaques) outside neurons in the brain and twisted strands of the protein tau (tangles) inside neurons are the hallmark pathologies of Alzheimers disease

The FDA does not recommend routine calcitonin testing or thyroid ultrasound screening solely for starting these medications in the absence of clinical findings