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Patients with significant gastrointestinal side effects, those in dose-escalation phases, or those with gastroparesis may be advised to withhold Rybelsus temporarily

Weight loss typically begins within 46 weeks and continues progressively with consistent medication use

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These findings suggest the potential broader applicability of semaglutide in smoking cessation, mainly due to its influence on reducing cravings and modulating dopamine pathways, which are also implicated in nicotine addiction